Grounded in human biology

Human disease arises from complex interactions between target cells, immune pathways, and tissue microenvironments. Whether in cancer or immune-mediated inflammatory disease, understanding when, where, and how potential targets are expressed in human tissues is essential for developing effective therapies.

Bluefin Biomedicine anchors discovery directly in human biology using proprietary proteomics-driven antigen discovery integrated with transcriptomic and bioinformatic analyses. We map target expression within complex human tissues to identify high-value biology with clear disease relevance.

This human tissue-anchored approach enables the identification of differentiated targets across immune pathways and tumor-intrinsic or tumor-associated mechanisms. Guided by these insights, we advanced first-in-class antibody medicines designed to address serious inflammatory and oncologic diseases with high unmet medical need.